• Stage I

Involvement of a single lymph node region (I) or of a single extra-lymphatic organ or site (IE)

•  Stage II

Involvement of two or more lymph node regions (number to be stated) on the same side of the diaphragm (II) or localised involvement of extra-lymphatic organ or site and of one or more lymph node regions on the same side of the diaphragm (IIE)

•  Stage III

Involvement of lymph node regions on both sides of the diaphragm (III) which may also be accompanied by localised involvement of extralymphatic organ or site (IIIE) or by involvement of the spleen (IIIE) or both (IIISE)

•  Stage IV

Diffuse or disseminated involvement of one or more extralymphatic organs or tissues with or without associated lymph node enlargement. Organ should be identified by symbols:

N Lymph nodes  /  L Lung  /  H Liver  /   P Pleural    /   O Bone   /   M Marrow  /  S Spleen

B SYMPTOM = Night sweats, unexplained weight loss >10% in the previous 6 months, unexplained pyrexia >38 0C. (Pruritis and alcohol induced pain can be associated with Lymphoma but are not B-symptoms)