Exercise and blood fat levels  

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Regular exercise has been shown to help control the body's levels of serum lipids and cholesterol. High serum fat levels have been particularly associated with greater risk of a more advanced and aggressive type of cancer with a higher risk of relapse after initial therapy. Men with prostate cancer with lower serum lipids have better prognostic features including lower PSA, lower grade (aggressiveness of cells) and lower stage (less advanced). These factors correlate with better outcomes. 

A clue to the mechanism of fat levels at least in prostate comes from the finding that lower serum fat levels correlated with lower testosterone. Circumstantial evidence is also emerging from studies giving people statins which also lower blood fat levels. Five of the largest randomised trials have demonstrated fewer colon, breast, and melanoma in long term users of statins compared to controls.