Carcinogens

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The section on what is cancer explained how certain dietary chemicals (carcinogens) can generate super oxide free radicals which damage DNA, rearrange the genes within our cells leading to the development of cancer.
 
Although patients with established cancer have already sustained the initiate DNA damage in order to mutate from benign to malignant cells, the cancer process can also be fuelled by continuing consumption of foods high in carcinogens. Further DNA damage can encourage the cancer to mutate into a more aggressive type or develop mechanism to hind from the body’s immunological defences. Avoiding carcinogens after cancer is also a benefit by reducing the risk of developing further cancers which are more likely in patients who may be more susceptible from a pre-existing genetic vulnerability or acquired damage from chemotherapy or radiotherapy.

There is a wide array of known carcinogens in our diet and probably many others which are unknown. 

The most notorious carcinogens found in our diet or environment are:-

Of this group of carcinogens, the most commonly investigated and discussed are the acrylamides. These chemicals are most often generated in the cooking process. They can start to be generated when food is cooked at 117°F (47°C) for three minutes or longer but the main culprits are grilling, high temperature oven baking or frying of meat, fats, and starchy carbohydrates such as potatoes making crisps, chips, and baked snacks.

The evidence for the risks of acrylamides stemmed from a report issued by the researchers at the Swedish National Food Administration and Stockholm University in 2002 which reported finding that acrylamides associated with high temperature cooking of carbohydrate-rich foods were linked to cancer. In response to the public concerns raised from this research the USA Food and Drug Administration (FDA) began to analyze a variety of U.S. food products for acrylamide (AA) concentrations and now publish regular league tables. There are also now moves to legislate the introduction of AA labelling on food products. This is however, proving difficult because the levels of AA depends not only on the foods we buy but the individual cooking process and can also vary considerably from one outlet to another. The table below from 2006 can, therefore only be used as a rough guide. It must also be remembered that total ingested AA is more important than the concentration in each foods; a small quantity of a food with high levels of AA such as a cream cracker is still safer than a large quantity of food with lower concentrations such as baked potatoes intake.

 

Acrylamide concentrations in common foods (FDA 2004 survey)

Often greater than 1000 ug/kg

Burnt barbequed meat

Grilled sweet potato crisps (chips)

Veggie chips potato snacks

Sweet Potato crisp (chips)

Roasted oat bran crackers

Veggie crisps (chips)

Usually between 500-1000 ug/kg

French fries

Pretzels

Processed baked potatoes

Ginger snap cookies

Toasted corn

Kettle crunch potato chips

Hash browns

Pitted ripe olives

Tortillas original tostadas

Low fat bruschetta vegetable crackers

Sesame snacks

Dried soup mix

Usually between 200-500 ug/kg

Butter flavoured popcorn

Crackers with peanut butter

Frozen potato skins (Frozen)

Corn flaked cereals

Corn chips

Cream crackers

Processed prune juice

Pepper toast

Coffee

 

General tips to avoid potential carcinogens:-

 


Further general information Your doctors and specialist nurses are in an ideal position to give you relevant information on your disease and treatment as they know your individual circumstances. Cancerbackup has a help line (0808 800 1234) and a prize winning video available in English, Italian, Urdu, Bengali, Gujarati & Hindi explaining Radiotherapy & Chemotherapy. Cancernet.co.uk has over 500 pages describing cancer, its management, practical tips and tool which patients, their carers and their doctors have found helpful during the cancer journey.


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